Citation

Endoh H, Kumagai Y, Baba H, Yamakura T, Taga K, Sato K, Fukuda S, Shimoji K. Brain Res. 1997; 767(1): 136-139.

Affiliation

Department of Anaesthesia, Niigata City Hospital, Niigata, Japan.

Copyright

(Copyright © 1997, International Brain Research Organization, Publisher Elsevier Publishing)

DOI

unavailable

PMID

9365025

Abstract

Minor brain injury was inflicted with a small hypodermic needle at four sites from the scalp 7 days before the production of convulsion by i.p. injection of 100 mg/kg lidocaine in mice. The latency to convulsion and survival rate were significantly longer and higher, respectively, in the brain-injured group than in the sham-operated one. Thus, the results suggest that a protective mechanism develops in the injured brain against asphyxia caused by lidocaine convulsion.

Language: en