Citation

Nishith P, Griffin MG, Poth TL. Biol. Psychiatry 2002; 51(11): 867-874.

Affiliation

Center for Trauma Recovery, University of Missouri, St. Louis, Missouri 63121, USA.

Copyright

(Copyright © 2002, Elsevier Publishing)

DOI

10.1016/S0006-3223(01)01346-4

PMID

12022959

Abstract

BACKGROUND: Chronic and inescapable trauma is implicated in the stress-induced analgesia (SIA) response. METHODS: A sample of 27 chronically battered women was compared with 28 trauma-exposed non-battered women on their SIA response at 1 month post-index assault. RESULTS: For the battered women sample, the SIA response at 1 month post-index assault was found to significantly predict an increase in posttraumatic stress disorder-related hyperarousal at 3 months post-index assault. Furthermore, the battered women showed a significant increase in depression symptoms from 1 to 3 months post-index assault compared with the non-battered women, who showed a significant decrease. CONCLUSIONS: The findings suggest that the chronic and inescapable nature of trauma exposure in the battered women might account for an SIA response that is qualitatively different from that seen in the non-battered women. It is suggested that the mechanism underlying the SIA response in battered women might be opioid mediated and that it might be responsible for the significant prediction of physiologic hyperarousal. Furthermore, this hyperarousal might moderate the relationship between the SIA response and depression.

Language: en