Citation

Nagata T, Harada D, Aoki K, Kada H, Miyata H, Kasahara H, Nakayama K. Psychiatry Clin. Neurosci. 2007; 61(6): 695-697.

Affiliation

Department of Psychiatry, Jikei University School of Medicine, Kashiwa Hospital, Kashiwa, Chiba, Japan. t.nagata@jikei.ac.jp

Copyright

(Copyright © 2007, John Wiley and Sons)

DOI

10.1111/j.1440-1819.2007.01737.x

PMID

18081636

Abstract

Anticonvulsants have been used for the treatment of impulsive aggression since the 1980s. A 50-year-old man suffered from irritability and agitation after developing a right ipsilateral frontal lobe infarction as a result of Moyamoya disease; these symptoms caused difficulties with his working and interpersonal relationships. The patient had been treated using multiple benzodiazepine agents for 2 years but his symptoms had not improved. However, after treatment with carbamazepine (CBZ; 200 mg) was begun, the patient's irritability and agitation gradually decreased. The efficacy of CBZ treatment in this patient suggests a method for controlling benzodiazepine-resistant impulsive aggression.

Language: en