Citation

Colella RF, Ratey JJ, Glaser AI. Int. J. Psychiatry Med. 1992; 22(4): 351-356.

Affiliation

Medfield State Hospital, Massachusetts.

Copyright

(Copyright © 1992, SAGE Publishing)

DOI

unavailable

PMID

1293064

Abstract

OBJECTIVE: This case examined the efficacy of buspirone therapy as a reductive technique for severe treatment resistant paramenstrual aggression. METHOD: Aggressive outbursts of an institutionalized mentally retarded adult were analyzed and correlated with menstrual cycling. Behavior was closely monitored, and after ineffective trials of antipsychotics, benzodiazepines and beta blockers, a trial of buspirone was initiated. RESULTS: Buspirone therapy resulted in a marked decrease in aggressive incidences, and substantial increases in desirable behaviors. As a result of the subjects improvement, doses of concurrent psychotropic medications were reduced or discontinued altogether. CONCLUSIONS: The authors conclude that buspirone is an effective pharmacotherapy for paramenstrual aggression in the developmentally disabled, and encourage similar experimentation when behavior seems to be otherwise untreatable.

Language: en