Citation

Matkevich VA, Simonenkov AP, Ostapenko IN, Zavadovskiĭ MM, Drendel SD, Kashtanova IS. Anesteziol. Reanimatol. 1995; (3): 16-20.

Vernacular Title

Primenenie serotonina-adipinata pri ostrykh peroral'nykh otravleniiakh.

Copyright

(Copyright © 1995, Meditsina)

DOI

unavailable

PMID

7544554

Abstract

Ninety-five patients with acute poisonings with psychotropic agents, barbiturates, amitriptyline, leponex, cholinolytics, and organophosphorus insecticides were treated by gastro-enteroadsorption making use of activated coal. In order to enhance propulsive function of the gastrointestinal tract, serotonin adipinate was repeatedly administered in a dose of 5 to 20 mg. Evacuation of the enteroadsorbent in the rectum was enhanced fivefold in comparison with a control group of similar patients administered traditional drugs (proserine, pituitrin, cerucal). As a result of such therapy, the toxicogenic phase of poisoning was shortened and mortality in the observed group reduced twofold in patients poisoned with psychotropic agents, 5.4 times in those with barbiturate poisoning, and 3.5 times in those with organophosphorus poisoning.

Language: ru