Citation

Kozhevnikov VS, Nabiullin RR, Lozovoĭ VP. Vestn. Akad. Med. Nauk SSSR 1991; (12): 3-8.

Vernacular Title

Prichiny vozniknoveniia i rol' immunodefitsita pri travme.

Copyright

(Copyright © 1991, Izd-vo Akademii Medit͡sinskikh Nauk SSSR)

DOI

unavailable

PMID

1801470

Abstract

The authors provide evidence for a concept of pathogenetic heterogeneity of posttraumatic immunodeficiency, analyze the causes and mechanisms underlying the development of cellular, combined or humoral immunodeficiency having different (sano-, genetic or pathogenetic) influence) in trauma. Cellular immunodeficiency marked by suppression of cellular effector functions is considered as a sanogenetic factor stimulating reparation processes and protecting from infection via humoral immunity activation. Combined immunodeficiency with suppressed humoral and cellular effector functions forms a pathogenetic basis for infectious complications of trauma. Humoral immunodeficiency marked by suppression of humoral effector functions and activation of cellular effector functions underlies inhibition of reparation processes and autodermograft lysis after autoplasty.

Language: ru