Citation

Ivanova-Chemishanska L, Vulcheva V, Chakurov E, Nachev Ch, Takeva Ts. Probl. Khig. 1975; 1: 25-30.

Vernacular Title

Promeni v gonadite i v sposobnostta za reproduktsiia na beli plukhove sled oralna

Copyright

(Copyright © 1975, Izdaca Natsionalniiat Tsentur po Khigiena, Meditsinska Ekologiia i Khranene)

DOI

unavailable

PMID

1236004

Abstract

Changes in the gonads and reproduction capacity of white rats following oral intoxication with maneb are studied. The preparation at doses 1/10, 1/50, 1/100 and 1/5000 LD50 is administered to the starting generation of white rats twice weekly. Changes in the gonads--biochemical, histological, histoenzymatic and electron microscopic--are established, as well as a capacity for reproduction of the starting I and II offspring. The results show a clearcut gonadotropic effect of the preparation, manifested by morphological changes in the starting generation, and by changes in fertility, gestation, survival and lactation of the starting I and II offspring.

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