Citation

Hill RM, Barer J, Hill LL, Butler CM, Harvey DJ, Horning MG. J. Pediatr. 1975; 87(1): 115-118.

Copyright

(Copyright © 1975, Elsevier Publishing)

DOI

unavailable

PMID

1151533

Abstract

An 18-month-old infant required six hospital admissions in a period of six months for episodes consisting of coughing, respiratory depression, hematemesis, coma, dehydration, and lesions about the mouth. A negative history of ingestion of toxins was repeatedly obtained from the family and two home inspection by the local Health Department failed to identify potential toxins. Metabolic work-up was entirely negative. Utilizing methods of GC-MS, metabolites of a-terpineol were isolated from infant urine on two admissions to the hospital. These metabolites were confirmed by mass spectrometry to be the same metabolites excreted by Sprague-Dawley rats injected with a-terpineol or pine oil. The child had no additional episodes after physical separation from the home environment.

Language: en