Citation

Chan CH, Leung AKh, Cheung YF, Chan PY, Au Yeung KW, Lai KY. Hong Kong Med. J. 2012; 18(4): 343-345.

Affiliation

B6, Intensive Care Unit, Queen Elizabeth Hospital, Jordan, Hong Kong.

Copyright

(Copyright © 2012, Hong Kong Academy of Medicine and the Hong Kong Medical Association)

DOI

unavailable

PMID

22865182

Abstract

Lithium salts have been used in treatment of depression and bipolar disorder for more than 50 years. Neurotoxic side-effects such as nystagmus, ataxia, tremor, fasciculation, clonus, seizure and even coma have been well described in the literature. We present a case of generalised peripheral neuropathy following lithium intoxication. It is a rare presentation with delayed onset and characterised by a rapid downhill course. Diagnosis was confirmed by nerve conduction tests, which showed axonal neuropathy. Despite the profound neurological effects of this toxicity, it is readily reversible with supportive care and the prognosis is good.

Language: en