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Journal Article

Citation

Demoranville LT, Verkouteren JR. Talanta 2013; 106: 375-380.

Affiliation

Surface and Microanalysis Science Division, National Institute of Standards and Technology, 100 Bureau Dr., Gaithersburg, MD 20899, United States; Chemistry Program, Centre College, 600 W. Walnut St., Danville, KY 40422, United States. Electronic address: leonard.demoranville@centre.edu.

Copyright

(Copyright © 2013, Elsevier Publishing)

DOI

10.1016/j.talanta.2013.01.011

PMID

23598140

Abstract

Ion mobility spectrometry has found widespread use for the detection of explosives and illicit drugs. The technique offers rapid results with high sensitivity and little sample preparation. As such, it is well suited for field deployed screening settings. Here the response of ion mobility spectrometers for three drug-facilitated sexual assault (DFSA) agents - flunitrazepam, ketamine, and MDMA - and related metabolites has been studied in the presence of a simulated sweat. While all three DFSA agents present certain challenges for qualitative identification, IMS can provide useful information to guide the early treatment and investigation of sexual assault cases. Used as a presumptive test, the identification of DFSA agents would later require confirmatory analysis by other techniques.


Language: en

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