Citation

Soyka M, Bondy B, Peuker B, Ackenheil M. J. Stud. Alcohol 1994; 55(4): 503-507.

Affiliation

Psychiatische Klinik und Poliklinik, Universität München, Federal Republic of Germany.

Copyright

(Copyright © 1994, Rutgers Center of Alcohol Studies)

DOI

unavailable

PMID

7934059

Abstract

An increased spiperone binding capacity in lymphocytes has been proposed as a possible biological marker for schizophrenia while in previous studies patients with alcohol dependence were shown to have a normal binding capacity. In a pilot study the spiperone binding capacity was studied in 8 patients with alcohol hallucinosis, 11 patients with acute drug-induced psychosis and 12 patients with other organic psychosis. An increased binding capacity, defined as > 4 fmol/l E6 cells, was found in only 1 patient with alcohol hallucinosis, 3 patients with drug-induced psychosis and 2 patients with other organic psychosis. Possible implications of these findings for future research are discussed.

Language: en