Citation

Wesner RB, Tanna VL, Palmer PJ, Thompson RJ, Crowe RR, Winokur G. J. Stud. Alcohol 1991; 52(6): 609-612.

Affiliation

Department of Psychiatry, College of Medicine, University of Iowa, Iowa City 52242.

Copyright

(Copyright © 1991, Rutgers Center of Alcohol Studies)

DOI

unavailable

PMID

1758189

Abstract

Unipolar depression and alcoholism were tested for genetic linkage to esterase-D at 13q14.1. Tight linkage to esterase-D was ruled out for three phenotypes using three models of penetrance: (1) unipolar depression and alcoholism taken together as affected, (2) unipolar depression alone as affected with alcoholism considered unaffected and (3) alcoholism alone as affected with unipolar depression considered unaffected. This study does not support an earlier finding of possible linkage between the esterase-D locus at 13q14.1 and alcoholism.

Language: en