Citation

Hanstock CC, Rothman DL, Shulman RG, Novotny EJ, Petroff OA, Prichard JW. J. Stud. Alcohol 1990; 51(2): 104-107.

Affiliation

Department of Applied Sciences in Medicine, University of Alberta, Edmonton, Canada.

Copyright

(Copyright © 1990, Rutgers Center of Alcohol Studies)

DOI

unavailable

PMID

2308346

Abstract

Ethanol in the human brain is readily observable by noninvasive 1H NMR spectroscopy. We have made such observations in a human subject with a time resolution per measurement of 6.5 min and volume resolution of 16 cc. The ethanol methyl proton signal is well separated from signals of other metabolites in 1H spectra from human brain and it is one of the most intense signals in such spectra when blood ethanol concentration is 0.1% (21.7 mM)--the legal definition of alcoholic intoxication in many jurisdictions. These properties, plus the fact that the ethanol signal can be further isolated from other resonances by spectral editing, open several possibilities for further investigation.

Language: en