Citation

Kent TA, Campbell JL, Pazdernik TL, Hunter R, Gunn WH, Goodwin DW. J. Stud. Alcohol 1985; 46(4): 357-359.

Copyright

(Copyright © 1985, Rutgers Center of Alcohol Studies)

DOI

unavailable

PMID

4033134

Abstract

Blood platelet uptake of 3H-serotonin (5HT uptake) was determined in a group of inpatient alcoholics who had just undergone detoxication (N = 19) and an age-matched group of nonalcoholic controls (N = 19). Mean 5HT uptake was 18% lower in the alcoholics (p less than .01). A 3-min 5HT uptake of less than 6 pmoles/10(7) platelets identified 58% of the alcoholics, but only 15% of the controls had a 5HT uptake lower than this value. These results support the hypothesis that serotonergic dysfunction may exist in alcoholics.

Language: en