Citation

Stanisavljevic S, Babcock AL. Clin. Orthop. Relat. Res. 1977; (125): 139-144.

Copyright

(Copyright © 1977, Springer)

DOI

unavailable

PMID

880755

Abstract

Multiple fractures occurred in 7 children treated with methotrexate for leukemia. Non-union or delayed union in spite of adequate immobilization also occurred in children on methotrexate. When the methotrexate was discontinued the fractures usually healed. Methotrexate appears to be a drug which inhibits osteogenesis, and may be promising in heterotopic ossification and related orthopedic conditions.

Language: en