Citation

Hindmarch I, Parrott AC. Br. J. Clin. Pharmacol. 1979; 8(4): 325-329.

Copyright

(Copyright © 1979, John Wiley and Sons)

DOI

unavailable

PMID

41548

PMCID

PMC1429832

Abstract

1. Repeated nocturnal doses of 30 mg clobazam and dipotassium chlorazepate 15 mg showed no significant effects compared to matching placebo on tests of psychomotor performance and serial subtraction of numbers given in the morning and afternoon of the day following treatment. 2. Both active preparations improved the perceived quality of sleep compared to placebo. 3. A reduction in rated anxiety scores was found with clobazam on the afternoon of the day following treatment together with an elevation of critical flicker fusion thresholds. 4. Dipotassium chlorazepate was found to impair performance of a low level conceptual task but not to influence performance at a more difficult level.

Language: en