Citation

Toczyska I, Płusa T. Pol. Merkuriusz Lek. 2015; 39(231): 157-161.

Vernacular Title

Toksyna Shiga oraz toksyna tężcowa jako potencjalna broń.

Affiliation

Military Institute of Medicine in Warsawa, Poland, Department of Internal Diseases, Pneumonology and Allergology, Central Clinical Hospital of the Ministry of National Defense.

Copyright

(Copyright © 2015, MEDPRESS - Polskiego Towarzystwa Lekarskiego)

DOI

unavailable

PMID

26449578

Abstract

Toxins produced by the bacteria are of particular interest as potential cargo combat possible for use in a terrorist attack or war. Shiga toxin is usually produced by shiga toxigenic strains of Escherichia coli (STEC - shigatoxigenic Escherichia coli). To infection occurs mostly after eating contaminated beef. Clinical syndromes associated with Shiga toxin diarrhea, hemorrhagic colitis, hemolytic uremic syndrome (HUS - hemolytic uremic syndrome) or thrombotic thrombocytopenic purpura. Treatment is symptomatic. In HUS, in which mortality during an epidemic reaches 20%, extending the kidney injury dialysis may be necessary. Exposure to tetanus toxin produced by Clostridium tetani, resulting in the most generalized tetanus, characterized by increased muscle tension and painful contractions of individual muscle groups. In the treatment beyond symptomatic behavior (among others spasticity medications, anticonvulsants, muscle relaxants) is used tetanus antitoxin and antibiotics (metronidazole choice). A common complication is acute respiratory failure - then it is necessary to implement mechanical ventilation.

Language: pl