Citation

Theorell T, de Manzano O, Lennartsson AK, Pedersen NL, Ullén F. Scand. J. Public Health 2016; 44(4): 354-360.

Affiliation

Department of Neuroscience, Karolinska Institutet, Sweden.

Copyright

(Copyright © 2016, Associations of Public Health in the Nordic Countries Regions, Publisher SAGE Publishing)

DOI

10.1177/1403494815626610

PMID

26825630

Abstract

OBJECTIVES: To examine the contribution of genetic factors to self-reported psychological demands (PD), skill discretion (SD) and decision authority (DA) and the possible importance of such influence on the association between these work variables and depressive symptoms.

METHODS: 11,543 participants aged 27-54 in the Swedish Twin Registry participated in a web survey. First of all, in multiple regressions, phenotypic associations between each one of the three work environment variables and depressive symptoms were analysed. Secondly, by means of classical twin analysis, the genetic contribution to PD, SD and DA was assessed. After this, cross-twin cross-trait correlations were computed between PD, SD and DA, on the one hand, and depressive symptom score, on the other hand.

RESULTS: The genetic contribution to self-reported PD, DS and DA ranged from 18% for decision authority to 30% for skill discretion. Cross-twin cross-trait correlations were very weak (r values <.1) and non-significant for dizygotic twins, and we lacked power to analyse the genetic architecture of the phenotypic associations using bivariate twin modelling. However, substantial genetic contribution to these associations seems unlikely.

CONCLUSIONS: Genetic contributions to the self-reported work environment scores were 18-30%.

Language: en