Citation

Jia W, Meng X, Qian Z, Hua Z, Li T, Liu C. Drug Test. Anal. 2016; 9(2): 248-255.

Affiliation

National Narcotics Laboratory, Drug Intelligence and Forensic Center of the Ministry of Public Security, Beijing, China.

Copyright

(Copyright © 2016, John Wiley and Sons)

DOI

10.1002/dta.1967

PMID

26968728

Abstract

This paper reports analytical properties of three cannabimimetic indazole and pyrazole derivatives seized from a clandestine laboratory. These three new synthetic cannabinoids include N-(1-adamantyl)-2-pentyl-2H-indazole-3-carboxamide (APINACA 2H-indazole analogue, 1), N-(1-adamantyl)-4-methyl-1-pentyl-5-phenyl-1H-pyrazole-3-carboxamide (AMPPPCA, 2), and N-(1-adamantyl)-1-(5-fluoropentyl)-4-methyl-5-phenyl-1H-pyrazole-3-carboxamide (5F-AMPPPCA, 3). These compounds were identified by liquid chromatography-quadrupole time-of-flight-mass spectrometry (LC-QTOF-MS), gas chromatography-time-of-flight-mass spectrometry (GC-TOF-MS), and nuclear magnetic resonance (NMR) spectroscopy. No analytical properties and pharmacological activities about compounds 1-3 have appeared until now, making this the first report on these compounds. Copyright © 2016 John Wiley & Sons, Ltd.

Copyright © 2016 John Wiley & Sons, Ltd.

Language: en