Citation

Copotoiu R, Cinca E, Collange O, Levy F, Mertes PM. Transfus. Clin. Biol. 2016; 23(4): 222-228.

Vernacular Title

Physiopathologie du choc hémorragique.

Affiliation

Service d'anesthésie-réanimation chirurgicale, hôpitaux universitaires de Strasbourg, nouvel hôpital civil, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France. Electronic address: paul-michel.mertes@chru-strasbourg.fr.

Copyright

(Copyright © 2016, Elsevier Publishing)

DOI

10.1016/j.tracli.2016.07.004

PMID

27567990

Abstract

This review addresses the pathophysiology of hemorrhagic shock, a condition produced by rapid and significant loss of intravascular volume, which may lead to hemodynamic instability, decreases in oxygen delivery, decreased tissue perfusion, cellular hypoxia, organ damage, and death. The initial neuroendocrine response is mainly a sympathetic activation. Haemorrhagic shock is associated altered microcirculatory permeability and visceral injury. It is also responsible for a complex inflammatory response associated with hemostasis alteration.

Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Language: fr