Citation

Bahloul M, Regaieg K, Chabchoub I, Kammoun M, Chtara K, Bouaziz M. Med Sante Trop 2017; 27(2): 214-221.

Vernacular Title

Les envenimations scorpioniques graves : physiopathologie et rôle de l’inflammation dans la défaillance multiviscérale.

Affiliation

Hôpital Habib Bourguiba, service de réanimation médicale, route El Ain Km 1, 3029 Sfax, Tunisie.

Copyright

(Copyright © 2017, John Libbey Eurotext)

DOI

10.1684/mst.2017.0688

PMID

28655685

Abstract

Scorpion stings occur on every continent except Antarctica. The correlation between young age and severity of clinical manifestations after this envenomation is well-established. Several studies have emphasized the relevance of pro-inflammatory mediators in the pathophysiological manifestations of human scorpion envenomation. Moreover, there is a significant association between pro-inflammatory cytokine levels in the blood and the severity of scorpion envenomation. Release of these cytokines increases the severity of the visceral damage induced by the direct action of the venom and the activation of both the sympathetic and parasympathetic nervous systems.

Language: en

Keywords

cytokines; inflammation; pathophysiology; scorpion envenomation