Citation

Yarlagadda A, Rosenblatt KP, Clayton AH. Innov. Clin. Neurosci. 2017; 14(5-6): 21-24.

Affiliation

Dr. Yarlagadda is Chief, Behavioral Health Services, McDonald Army Health Center in Newport News, Virginia, and Assistant Professor, Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia.

Copyright

(Copyright © 2017, Matrix Medical Communications)

DOI

unavailable

PMID

28979823

Abstract

The rate of completed suicides continues to rise across nations, cultures, socioeconomic classes, age groups, sexes, military personnel, veterans, and civilians from different backgrounds. Most concerning is the absence of diagnosed mental health disorders in the majority of these cases, per current literature reports. Efforts in the identification and possible prevention of this ultimate, tragic act of self-destruction have been minimally successful. In this article, the authors discuss the possible biological mechanisms including the role for potential markers, single nucleotide polymorphisms (SNPs), and their association with suicidal behaviors.

Language: en

Keywords

CYP2C19; CYP2D6; Single nucleotide polymorphisms, SNPs; biomarkers; suicide risk