Citation

Zeng Y, Ma JL, Chen L. Fa Yi Xue Za Zhi 2017; 33(1): 38-41.

Affiliation

Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China.

Copyright

(Copyright © 2017, Si fa bu Si fa jian ding ke xue ji shu yan jiu suo)

DOI

10.3969/j.issn.1004-5619.2017.01.010

PMID

29231008

Abstract

Under hypoxia condition, microRNA （miRNA） can interact with transcription factors for regulating the cell metabolism, angiogenesis, erythropoiesis, cellular proliferation, differentiation and apoptosis. The biological processes above may play an important role in mechanical asphyxia death. This article reviews the regulating function of miRNA under hypoxia condition and the influence of hypoxia to biosynthesis of miRNA, which may provide some new ideas to the research of miRNA on determining the cause of mechanical asphyxia death in the field of forensic medicine.

Copyright© by the Editorial Department of Journal of Forensic Medicine.

Language: zh

Keywords

anoxia; asphyxia; cause of death; forensic pathology; microRNA; review