Citation

Ciuffreda KJ, Joshi NR, Truong JQ. Concussion 2017; 2(3): CNC36.

Affiliation

Brain Injury Research Clinic, SUNY/State College of Optometry, 33 West 42nd Street, New York City, NY 10036, USA.

Copyright

(Copyright © 2017, The Drake Foundation, Publisher Future Medicine)

DOI

10.2217/cnc-2016-0029

PMID

30202579

PMCID

PMC6094691

Abstract

The pupillary light reflex represents an optimal visual system to investigate and exploit in the mild traumatic brain injury (mTBI) population. Static and dynamic aspects of the pupillary light reflex were investigated objectively and quantitatively in the mTBI population. Pupillary responsivity was found to be significantly delayed, slowed and reduced, but symmetrical in nature, and with a smaller baseline diameter, as compared with normals. Several pupillary parameters also discriminated between those with versus without photosensitivity. Thus, dynamic pupillometry provides several objective biomarkers for the presence of mTBI and photosensitivity, gives insight into the global sites of neurological dysfunction and possible related mechanisms, and should result in improved patient care.

Language: en

Keywords

PLR; mTBI; mild traumatic brain injury; photosensitivity; pupillary light reflex