|
Citation
|
Stojanoski B, Benoit A, Van Den Berg N, Ray LB, Owen AM, Shahidi Zandi A, Quddus A, Comeau FJE, Fogel SM. Sleep 2019; 42(1): ePub. |
|
Abstract
|
STUDY OBJECTIVES: The behavioural and cognitive consequences of severe sleep deprivation are well understood. Surprisingly, relatively little is known about the neural correlates of mild and acute sleep restriction on tasks that require sustained vigilance for prolonged periods of time during the day.
METHODS AND RESULTS: Event-related potential (ERP) paradigms can reveal insight into the neural correlates underlying visual processing and behavioral responding that is impaired with reduced alertness, as a consequence of sleep loss. Here, we investigated the impact of reduced vigilance following at-home mild sleep restriction to better understand the associated behavioural consequences and changes in information processing revealed by ERPs. As expected, vigilance was reduced (e.g., increased lapses, response slowing), that increased over the course of the experiment in the "sleep restricted" (5 hours sleep) compared to the "sleep-extension" (9 hours sleep) condition. Corresponding to these lapses, we found decreased positivity of visually-evoked potentials (VEP) in the Sleep Restriction vs. Sleep Extension condition emerging from 316 to 449 ms, maximal over parietal/occipital cortex. We also investigated electrophysiological signs of motor-related processing by comparing lateralized readiness potentials (LRP), and found reduced positivity of LRPs in the Sleep Restriction vs. Sleep Extension condition at 70-40ms before, and 115-158ms after a response was made.
CONCLUSIONS: These results suggest that even a single night of mild sleep restriction can negatively impact vigilance, reflected by reduced processing capacity for decision making, and dulls motor preparation and execution.
Language: en |