Citation

Câmara-Costa H, Francillette L, Opatowski M, Toure H, Brugel D, Laurent-Vannier A, Meyer P, Dellatolas G, Watier L, Chevignard M. J. Head Trauma Rehabil. 2019; ePub(ePub): ePub.

Affiliation

Université Paris-Saclay, Université Paris-SUD, UVSQ, CESP, INSERM, Paris, France (Drs Câmara-Costa and Dellatolas); Sorbonne Université, Laboratoire d'Imagerie Biomédicale, LIB, Paris, France (Drs Câmara-Costa, Dellatolas, and Chevignard and Ms Francillette); Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases (B2PHI), INSERM, UVSQ, Institut Pasteur, Université Paris-Saclay, Paris, France (Ms Opatowski and Dr Watier); Rehabilitation Department for Children with Acquired Neurological Injury, and Outreach team for Children and Adolescents With Acquired Brain Injury, Saint Maurice Hospitals, Saint Maurice, France (Drs Toure, Brugel, Laurent-Vannier, and Chevignard); Paediatric Anesthesiology Department, Hôpital Necker Enfants Malades, Paris, France (Dr Meyer); Faculté de Médecine René Descartes Paris 5, Paris, France (Dr Meyer); and Groupe de Recherche Clinique Handicap Cognitif et Réadaptation (HanCRe), Sorbonne Université, Paris, France (Dr Chevignard).

Copyright

(Copyright © 2019, Lippincott Williams and Wilkins)

DOI

10.1097/HTR.0000000000000502

PMID

31246880

Abstract

OBJECTIVE: To investigate presence of and factors associated with self- and parent-reported fatigue 7 years after severe childhood traumatic brain injury (TBI) in the prospective longitudinal study TGE (Traumatisme Grave de l'Enfant-severe childhood trauma).

METHODS: Self-reports and/or parent reports on the Multidimensional Fatigue Scale were collected for 38 participants (aged 7-22 years) 7 years after severe childhood TBI, and 33 controls matched for age, gender, and parental educational level. The data collected included sociodemographic characteristics, age at injury and injury severity scores, overall disability (Glasgow Outcome Scale Extended), intellectual outcome (Wechsler scales), and questionnaires assessing executive functions, health-related quality of life, behavior, and participation.

RESULTS: Fatigue levels were significantly worse in the TBI than in the control group, especially for cognitive fatigue. Correlations of reported fatigue with age at injury, gender, TBI severity, and intellectual ability were moderate and often not significant. Fatigue was significantly associated with overall level of disability (Glasgow Outcome Scale Extended) and with all questionnaires completed by the same informant.

CONCLUSION: High levels of fatigue were reported by 30% to 50% of patients 7 years after a severe childhood TBI. Reported fatigue explained more than 60% of the variance of reported health-related quality of life by the same informant (patient or parent).

Language: en