Citation

Dech RT, Bishop SA, Neary JP. J. Sci. Med. Sport 2019; ePub(ePub): ePub.

Affiliation

Faculty of Kinesiology & Health Studies, University of Regina, Canada. Electronic address: Patrick.neary@uregina.ca.

Copyright

(Copyright © 2019, Sports Medicine Australia, Publisher Elsevier Publishing)

DOI

10.1016/j.jsams.2019.06.007

PMID

31349959

Abstract

INTRODUCTION: Concussion diagnosis and rehabilitation management has become a prevalent area of research, and yet much is still unknown about these complex injuries. Historically, exercise prescription post-concussion was conservatively used for rehabilitation due to the suspected harmful effects that exercise can have on damaged neurons, and increase in symptoms. However, there has been a shift to implement exercise earlier into recovery as several studies have demonstrated positive outcomes.

OBJECTIVE: The objective of this literature review is to update the reader about new advances in concussion research related to the beneficial effects of physical activity from both a neurometabolic and a broader physiological perspective, using gene expression as a vehicle to demonstrate why and how physical activity has the capacity to optimize recovery from a cellular perspective. To further this clinical guideline, the evidence must continue to support these positive outcomes from an inductive and deductive physiologic approach (i.e., the clinical evidence aligned from a micro- to macroscopic approach and vice versa).

DESIGN: Narrative review.

METHODS: Pubmed and Medline were used with the following key words: concussion and, physical activity, neurometabolic, gene regulation, trauma, nervous system, mild head injury, acute exercise, cellular physiology and pathophysiology.

CONCLUSION: It is our contention that understanding the cellular perspective will help guide clinical management, and promote research into post-concussion exercise.

Copyright © 2019 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Language: en

Keywords

Acute exercise; Cellular physiology; Mild head injury; Nervous system; Physical activity; Trauma