Citation

Stuart S, Parrington L, Martini DN, Kreter N, Chesnutt JC, Fino P, King LA. J. Neurotrauma 2019; ePub(ePub): ePub.

Affiliation

Oregon Health and Science University, 6684, Department of Neurology, Portland, Oregon, United States; kingla@ohsu.edu.

Copyright

(Copyright © 2019, Mary Ann Liebert Publishers)

DOI

10.1089/neu.2019.6450

PMID

31354032

Abstract

Balance and mobility issues are common non-resolving symptoms following mild traumatic brain injury (mTBI). Current approaches for evaluating balance and mobility following an mTBI can be subjective and sub-optimal as they may not be sensitive to subtle deficits, particularly in those with chronic mTBI. Wearable inertial measurement units (IMU) allow objective quantification of continuous mobility outcomes in natural free-living environments. This study aimed to explore free-living mobility (physical activity and turning) of healthy and chronic mild traumatic brain injury (mTBI) participants using a single IMU. Free-living mobility was examined in twenty-three healthy control (48.56±23.07years) and twenty-nine symptomatic mTBI (40.2±12.1years) participants (average 419days post-injury, persistent balance complaints) over one week, using a single IMU placed at the waist. Free-living mobility was characterized in terms of Macro (physical activity volume, pattern and variability) and Micro-level (discrete measures of turning) features. Macro-level outcomes showed those with chronic mTBI had similar quantities of mobility compared to controls. Micro-level outcomes within walking bouts showed that chronic mTBI participants had impaired quality of mobility. Specifically, people with chronic mTBI made larger turns, had longer turning durations, slower average and peak velocities (all p<.001) and greater turn variability compared to controls.

RESULTS highlighted that the quality, rather than quantity of mobility differentiated chronic mTBI from controls. Our findings support the use of free-living IMU continuous monitoring to enhance understanding of specific chronic mTBI-related mobility deficits. Future work is required to develop an optimal battery of free-living measures across the mTBI spectrum to aid application within clinical practice.

Language: en

Keywords

LOCOMOTOR FUNCTION; OUTCOME MEASURES; REHABILITATION; TRAUMATIC BRAIN INJURY