Citation

Chuquilín-Arista F, Álvarez-Avellón T, Menéndez-González M. J. Geriatr. Psychiatry Neurol. 2019; ePub(ePub): ePub.

Affiliation

Department of Morphology and Cell Biology, Universidad de Oviedo, Asturias, Spain.

Copyright

(Copyright © 2019, SAGE Publishing)

DOI

10.1177/0891988719874130

PMID

31597514

Abstract

BACKGROUND: Identifying neuropsychiatric disorders is essential for prompt treatment to reduce morbidity. Among these disorders, anxiety and depression have been frequently associated with Parkinson disease (PD), particularly among elderly population.

OBJECTIVE: The objective of this study is to determine the prevalence of anxiety and depression in a series of community-based PD cases in Spain, their relationship with different clinical and sociodemographic characteristics, and quality of life.

METHODS: This is an observational, descriptive, survey-based study with 95 community-based patients with PD diagnosis at different disease stages. Anxiety and depression were assessed using the State-Trait Anxiety Inventory and the Beck Depression Inventory II, respectively. Quality of life was assessed using the Parkinson's Disease Questionnaire 39.

RESULTS: The prevalence of depression and anxiety was 32.63% and 68.42%, respectively. Concomitant depression and anxiety were observed in 31.58% of patients. Patients with longer than 10 years' PD duration had an increased risk of depression. We found a relationship between the presence of anxiety, depression, and the patient's quality of life.

CONCLUSIONS: Depression is present in one-third and anxiety in two-thirds of PD cases in community settings in Spain. Depression and anxiety have a very negative impact on quality of life in PD. Both anxiety and depression are independent from sociodemographic characteristics, patient's comorbidities, or antiparkinsonian treatments; presenting as intrinsic symptoms in PD.

Language: en

Keywords

Parkinson disease; anxiety; depression; quality of life