Citation

Karr JE, Iverson GL, Huang SJ, Silverberg ND, Yang CC. J. Neurotrauma 2019; ePub(ePub): ePub.

Affiliation

Taipei City Hospital, 38010, Holistic Social Preventive and Mental Health Center, Taipei, Taiwan; yangyang@nccu.edu.tw.

Copyright

(Copyright © 2019, Mary Ann Liebert Publishers)

DOI

10.1089/neu.2019.6834

PMID

31797728

Abstract

The objective of this study was to compare patients with acute-to-subacute MTBI on post-concussion symptom reporting based on whether they retrospectively endorsed experiencing pre-injury anxiety or depression. Patients with MTBI (n=297; 40.4% men; M=38.2 years old, SD=14.0, range=17-65), referred from an emergency department in Taipei, Taiwan, were seen in a neurosurgical outpatient clinic on average 7.7 days since injury (SD=5.7, range=0-21 days), at which time they completed a checklist of post-concussion symptoms. Patients rated their current symptom severity and retrospectively rated their pre-injury symptom severity on 15 physical, cognitive, and emotional symptoms. Patients were grouped based on whether they did or did not endorse mild or greater pre-injury anxiety or depression on this scale. Those endorsing pre-injury anxiety or depression had greater pre-injury (all p's<.001, d range: 0.92-2.03) and post-injury (all p's<.001, d range: 0.65-1.00) symptom severity. However, when analyzing perceived change in symptoms (i.e., post-injury ratings minus pre-injury ratings), only perceived change in cognitive symptoms differed across groups (p=.018, d=0.29), which became non-significant after controlling for gender. Greater post-concussion symptom severity in patients endorsing pre-existing mental health problems may be mostly attributable to elevated symptoms before injury. These findings demonstrate the clinical value of retrospective pre-injury symptom assessment in MTBI management. Greater post-concussion symptom severity in patients with pre-injury mental health problems may represent a continuation of greater pre-injury symptom severity rather than a greater increase in symptom severity after MTBI.

Language: en

Keywords

ADULT BRAIN INJURY; NEUROPSYCHOLOGY; REHABILITATION; TRAUMATIC BRAIN INJURY