Citation

Li X, Pan Y, Fang Z, Lei H, Zhang X, Shi H, Ma N, Raine P, Wetherill R, Kim JJ, Wan Y, Rao H. Neuroimage 2019; ePub(ePub): ePub.

Affiliation

Key Laboratory of Applied Brain and Cognitive Sciences, School of Business and Management, Shanghai International Studies University, Shanghai, China; Center for Functional Neuroimaging, Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. Electronic address: hengyi@pennmedicine.upenn.edu.

Copyright

(Copyright © 2019, Elsevier Publishing)

DOI

10.1016/j.neuroimage.2019.116495

PMID

31887425

Abstract

The Balloon Analogue Risk Task (BART) provides a reliable and ecologically valid model for the assessment of individual risk-taking propensity and is frequently used in neuroimaging and developmental research. Although the test-retest reliability of risk-taking behavior during the BART is well established, the reliability of brain activation patterns in response to risk-taking during the BART remains elusive. In this study, we used functional magnetic resonance imaging (fMRI) and evaluated the test-retest reliability of brain responses in 34 healthy adults during a modified BART by calculating the intraclass correlation coefficients (ICC) and Dice's similarity coefficients (DSC). Analyses revealed that risk-induced brain activation patterns showed good test-retest reliability (median ICC = 0.62) and moderate to high spatial consistency, while brain activation patterns associated with win or loss outcomes only had poor to fair reliability (median ICC = 0.33 for win and 0.42 for loss). These findings have important implications for future utility of the BART in fMRI to examine brain responses to risk-taking and decision-making.

Copyright © 2019. Published by Elsevier Inc.

Language: en

Keywords

Balloon analogue risk task (BART); Intraclass correlation coefficient (ICC); Test-retest reliability; fMRI