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Citation |
Bloomfield MAP, Yusuf FNIB, Srinivasan R, Kelleher I, Bell V, Pitman A. Lancet Psychiatry 2020; ePub(ePub): ePub. |
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Affiliation |
Epidemiology and Applied Clinical Research Department, University College London, London, UK; The Huntley Centre, Camden and Islington NHS Foundation Trust, London, UK; National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College Hospital, London, UK. |
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Copyright |
(Copyright © 2020, Elsevier Publishing) |
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DOI |
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PMID |
32004444 |
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Abstract |
Developmental trauma is associated with an increased risk of psychosis and predicts poor prognosis. Despite this association, little is known about which treatments work best for survivors of developmental trauma with psychosis. We sought to do the first review, to our knowledge, to investigate treatments for people with psychotic and dissociative symptoms who have a history of developmental trauma. We searched MEDLINE, PsychINFO, and Google Scholar for studies reporting psychological and pharmacological treatments of psychotic or dissociative symptoms in adult survivors of developmental trauma. We identified 24 studies, most of which investigated various modalities of psychotherapy with two case reports of pharmacological treatments. There is preliminary evidence in favour of third wave cognitive therapies. However, because of low methodological quality and reporting in most of the studies found, it remains unknown which treatments are most effective in this clinical group. Nonetheless, our findings of potential treatment targets, including emotion regulation, acceptance, interpersonal skills, trauma re-processing, and the integration of dissociated ego states, could guide future work in this area. Language: en |