Citation

Tondo L, Vazquez GH, Baldessarini RJ. Psychiatr. Clin. North Am. 2020; 43(1): 83-93.

Affiliation

International Consortium for Research on Mood & Psychotic Disorders, McLean Hospital, Belmont, MA, USA; Mailman Research Center 3, McLean Hospital, 115 Mill Street, Belmont, MA 02478-9106, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

Copyright

(Copyright © 2020, Elsevier Publishing)

DOI

10.1016/j.psc.2019.10.008

PMID

32008690

Abstract

Mixed features of the opposite nominal mood-polarity are increasingly recognized in both depressive and [hypo]manic phases of major affective disorders. They are associated with major increases of risk of suicidal behaviors. The authors reviewed the association of suicidal behavior with mixed features in both major depressive and bipolar disorders, as well as potentially relevant adverse effects of antidepressant treatment and use of alternative treatments aimed at minimizing agitation and suicidal risk.

Copyright © 2019 Elsevier Inc. All rights reserved.

Language: en

Keywords

Attempt; Depression; Ideation; Lethality; Mixed features; Risk rates; Suicide; Treatment