Citation

Muthumalage T, Friedman MR, McGraw MD, Ginsberg G, Friedman AE, Rahman I. Toxics (Basel) 2020; 8(2): e25.

Affiliation

Department of Environmental Medicine, University of Rochester Medical Center Box 850, 601 Elmwood Avenue, Rochester, NY 14642, USA.

Copyright

(Copyright © 2020, MDPI: Multidisciplinary Digital Publishing Institute)

DOI

10.3390/toxics8020025

PMID

32260052

Abstract

The Centers for Disease Control declared e-cigarette, or vaping, product use-associated lung injury (EVALI) a national outbreak due to the high incidence of emergency department admissions and deaths. We have identified chemical constituents in e-cig counterfeit cartridges and compared these to medical-grade and CBD containing cartridges. Apart from vitamin E acetate (VEA) and tetrahydrocannabinol (THC), other potential toxicants were identified including solvent-derived hydrocarbons, silicon conjugated compounds, various terpenes, pesticides/plasticizers/polycaprolactones, and metals. This study provides additional insights into the chemicals associated with EVALI cartridges and thus may contribute to the underlying disease mechanism of acute lung injury.

Language: en

Keywords

EVALI; THC; VAPI; Vaping; cannabis; e-cigarette; lipoid-pneumonia