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Citation
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Eyigor S, Kutsal YG, Toraman F, Durmus B, Gokkaya KO, Aydeniz A, Paker N, Borman P. Exp. Aging Res. 2020; ePub(ePub): ePub. |
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Abstract
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BACKGROUND: To investigate the association of polypharmacy with physical function, nutritional status, and depression in the elderly.
METHOD: The study included 675 people aged over 65 years from 8 centers in various geographical regions. The polypharmacy status was categorized as non-polypharmacy (0-4 drugs), polypharmacy (≥5 drugs). The subjects' physical function was assessed based on their "physical activity levels, Holden ambulation scores, gait speeds, and hand grip strengths"; their nutritional status based on the "Mini Nutritional Assessment (MNA)"; and their psychological status based on the "Center for Epidemiologic Studies Depression Scale -CES-D".
RESULTS: The presence of polypharmacy in this population was found to be 30% (n = 203). A statistically significant difference was found between the groups on the level of physical activity, Holden ambulation score, and nutrition status (p < .05). There was a statistically significant difference between the groups also on hand grip strength, MNA score, Charlson score (p < .05).
CONCLUSION: Polypharmacy was observed to have a significant association with physical function, nutrition, and depression in the elderly aged ≥ 65 years.
Language: en |