Citation

Schmutte T, Olfson M, Maust DT, Xie M, Marcus SC. Alzheimers Dement. 2021; ePub(ePub): ePub.

Copyright

(Copyright © 2021, Alzheimer's Association, Publisher Elsevier Publishing)

DOI

10.1002/alz.12390

PMID

unavailable

Abstract

INTRODUCTION: Receiving a diagnosis of Alzheimer's disease or related dementias (ADRD) can be a pivotal and stressful period. We examined the risk of suicide in the first year after ADRD diagnosis relative to the general geriatric population.

METHODS: We identified a national cohort of Medicare fee-for-service beneficiaries aged ≥ 65 years with newly diagnosed ADRD (n = 2,667,987) linked to the National Death Index.

RESULTS: The suicide rate for the ADRD cohort was 26.42 per 100,000 person-years. The overall standardized mortality ratio (SMR) for suicide was 1.53 (95% confidence interval [CI] = 1.42, 1.65) with the highest risk among adults aged 65 to 74 years (SMR = 3.40, 95% CI = 2.94, 3.86) and the first 90 days after ADRD diagnosis. Rural residence and recent mental health, substance use, or chronic pain conditions were associated with increased suicide risk.

DISCUSSION: Results highlight the importance of suicide risk screening and support at the time of newly diagnosed dementia, particularly for patients aged < 75 years.

Language: en

Keywords

dementia; suicide; Alzheimer's disease; mental disorder