Citation

Bitsika V, Sharpley CF, McMillan ME, Jesulola E, Agnew LL. Front. Psychiatry 2021; 12: e533722.

Copyright

(Copyright © 2021, Frontiers Media)

DOI

10.3389/fpsyt.2021.533722

PMID

34867491

PMCID

PMC8637154

Abstract

In order to evaluate the effects of specific forms of childhood maltreatment (CM) upon adult C-reactive protein (CRP) concentrations, and to further describe the potentially confounding role that recent life stress and depression hold in that relationship, 221 participants from rural Australia (M age = 44yr, SD = 17.8yr) completed self-report questionnaires and provided a blood sample. There were no sex differences in any variables across the 91 males and 130 females, but depression status did confound the association between global CM and CRP. The specific aspect of CM was identified as physical and mental health abuse, and this was significantly associated with CRP level in participants with depressive symptoms and those without. There was no significant confound from recent life stressors.

RESULTS hold implications for the diagnosis of CM-related CRP elevation and (potentially) depression.

Language: en

Keywords

abuse; depression; childhood; CRP - C-reactive protein; maltreatment against children