Citation

Zhang L, Cai H, Bai W, Zou SY, Feng KX, Li YC, Liu HZ, Du X, Zeng ZT, Lu CM, Zhang L, Mi WF, Ding YH, Yang JJ, Jackson T, Cheung T, Su Z, An FR, Xiang YT. J. Affect. Disord. 2022; ePub(ePub): ePub.

Copyright

(Copyright © 2022, Elsevier Publishing)

DOI

10.1016/j.jad.2022.03.042

PMID

35337925

PMCID

PMC8938301

Abstract

BACKGROUND: The COVID-19 pandemic is associated with an increased risk of mental health problems including suicide in many subpopulations, but its influence on stable patients with major depressive disorder (MDD) has been studied fleetingly. This study examined the one-year prevalence of suicidality including suicidal ideation (SI), suicide plans (SP), and suicide attempts (SA) as well as their correlates in clinically stable MDD patients during the COVID-19 pandemic.

METHODS: A cross-sectional, observational study was conducted between October 1, 2020, and October 15, 2021 in six tertiary psychiatric hospitals. Socio-demographic information, clinical data and one-year prevalence of suicidality were recorded.

RESULTS: Altogether, 1718 participants who met the eligibility criteria were included. The overall one-year prevalence of suicidality during the COVID-19 pandemic was 68.04% (95% confidence intervals (CI) =65.84-70.25%), with one-year SI prevalence of 66.4% (95%CI = 64.18%-68.65%), SP prevalence of 36.26% (95%CI = 33.99%-38.54%), and SA prevalence of 39.35% (95%CI = 37.04%-41.66%). Binary logistic regression analyses revealed male gender, married marital status, college education level and above and age were negatively associated with risk of suicidality. Urban residence, unemployed work status, experiences of cyberbullying, a history of suicide among family members or friends, and more severe fatigue, physical pain, and residual depressive symptoms were positively associated with risk of suicidality.

CONCLUSIONS: Suicidality is common among clinically stable MDD patients during the COVID-19 pandemic. Regular suicide screening and preventive measures on suicide should be provided to clinically stable MDD patients during the pandemic.

Language: en

Keywords

Suicidality; Major depressive disorder; COVID-19 pandemic