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Citation |
Arbogast KB, Ghosh RP, Corwin D, McDonald CC, Mohammed FN, Margulies S, Barnett I, Master C. J. Neurotrauma 2022; ePub(ePub): ePub. |
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Copyright |
(Copyright © 2022, Mary Ann Liebert Publishers) |
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DOI |
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PMID |
35785959 |
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Abstract |
Visual and vestibular deficits, as measured by a visio-vestibular exam (VVE), are markers of concussion in youth. Little is known about VVE evolution post-injury, nor influence of age or sex on trajectory. The objective was to describe the time trend of abnormal VVE elements after concussion. Two cohorts, 11-18 years, were enrolled; healthy adolescents (n=171) from a high school with VVE assessment prior to or immediately after their sport seasons and; concussed participants (n=255) from a specialty care concussion program, with initial assessment <=28 days from injury and VVE repeated throughout recovery during clinical visits. The primary outcome, compared between groups, is the time course of recovery of the VVE exam, defined as the probability of an abnormal VVE (>2/9 abnormal elements) and modelled as a cubic polynomial of days after injury. We explored whether probability trajectories differed by: age (<14 years vs 14+ years), sex, concussion history (0 versus 1+), and days from injury to last assessment (<28 days vs 29+ days). Overall, abnormal VVE probability peaked at 0.57 at day 8 post-injury, compared to an underlying prevalence of 0.083 for uninjured adolescents. Abnormal VVE probability peaked higher for those 14+ years, female, with a concussion history and whose recovery course was longer than 28 days post- injury, compared with their appropriate strata subgroups. Females and those <14 years demonstrated slower resolution of VVE abnormalities. VVE deficits are common in adolescents after concussion and the trajectory of resolution varies by age, sex and concussion history. These data provide insight to clinicians managing concussions on the timing of deficit resolution after injury. Language: en |
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Keywords |
HUMAN STUDIES; ASSESSMENT TOOLS; PEDIATRIC BRAIN INJURY |