Citation

Di Vara S, Guerrera S, Valeri G, Vicari S. Neurocase 2022; 28(4): 369-374.

Copyright

(Copyright © 2022, Informa - Taylor and Francis Group)

DOI

10.1080/13554794.2022.2130804

PMID

36369699

Abstract

Childhood Disintegrative Disorder (CDD) is a rare condition characterized by regression of developmental and behavioral functioning after a period of apparently normal development, with an age of onset around 4 years. CDD is not included within the latest edition of the Diagnostic and Statistical Manual of Mental Disorders. We present a case report of an 11-year-old male who achieved normal development for up to 7 years followed by a deterioration of previously acquired linguistic, intellectual, and social skills. Following treatment with lithium carbonate combined with risperidone, the patient experienced a reduction in irritability and aggression. CDD is a rare condition; therefore, the data presented may be useful to investigate its characteristics of the onset, to improve the understanding of the aspects of differentiation from the Autism Spectrum Disorder and finally to propose the possibility of treatment.

Language: en

Keywords

case report; Autism Spectrum Disorder; CDD; lithium carbonate