Citation

Mank A, van Maurik IS, van Harten AC, Rhodius-Meester HFM, Teunissen CE, van Berckel BNM, Berkhof J, van der Flier WM, Rijnhart JJM. Alzheimers Dement. (Amst) 2022; 14(1): e12389.

Copyright

(Copyright © 2022, The Author(s), Publisher Elsevier Publishing)

DOI

10.1002/dad2.12389

PMID

36579132

PMCID

PMC9780509

Abstract

INTRODUCTION: We studied life satisfaction across Alzheimer's disease (AD) stages and studied mobility and meaningful activities as mediators of the associations between these AD stages and life satisfaction.

METHODS: In this cross-sectional study, we included n = 269 amyloid-positive patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and AD dementia from the Amsterdam Dementia Cohort. Life satisfaction was measured with the satisfaction with life scale. The mediating role of transportation, work, sports, and hobbies on life satisfaction was examined in single and multiple mediator models.

RESULTS: Patients with dementia are less satisfied with life compared to SCD and MCI. These differences in life satisfaction are explained by reduced participation in meaningful activities, which in turn, was largely attributable to decreased transportation use.

DISCUSSION: Our findings suggest that improving access to transportation, therewith allowing participation in meaningful activities help to maintain life satisfaction and may be an important target for intervention.

Language: en

Keywords

dementia; mobility; life satisfaction; Alhzeimer's disease; mild cognitive impairment; subjective cognitive decline