Citation

Xie M, Zou X, Xie Y, Hu L, Tang Y, Cai J, Kuang Y, Zhu L, Zou M, Wang Q. Front. Psychiatry 2023; 14: e1221529.

Copyright

(Copyright © 2023, Frontiers Media)

DOI

10.3389/fpsyt.2023.1221529

PMID

37810605

PMCID

PMC10551446

Abstract

INTRODUCTION: Stressful global situation due to the COVID-19 pandemic caused a tremendous impact on mental health in hospitalized patients with schizophrenia. The mediating roles of psychological impact related to COVID-19, sleep quality, and psychological distress were investigated in the association between childhood trauma and suicidal risk in hospitalized patients with schizophrenia.

METHODS: We analyzed cross-sectional data of 147 patients with schizophrenia and 189 healthy controls (HCs).

RESULTS: Histories of childhood trauma and schizophrenia were good predictors of COVID-19-related psychological impact, global sleep quality, and psychological distress. Moreover, the series mediation model showed that the effect of childhood trauma on suicidal risk in hospitalized patients with schizophrenia was totally sequential mediated by the psychological impact of COVID-19, sleep quality, and psychological distress.

CONCLUSION: Clinicians need to recognize the increased suicidal risk associated with COVID-19-related psychological distress in schizophrenia patients with a history of childhood trauma.

Language: en

Keywords

COVID-19 pandemic; schizophrenia; suicide risk; sleep quality; childhood trauma; post-traumatic stress symptoms