Citation

Shi M, Zeng M, Jian T, Yu G, Genjiafu A, Zhang X, Guo L, Shang R, Zhou Z, Zhang T, Jian X, Kan B. Front. Public Health 2023; 11: e1309708.

Copyright

(Copyright © 2023, Frontiers Editorial Office)

DOI

10.3389/fpubh.2023.1309708

PMID

38145083

PMCID

PMC10740189

Abstract

OBJECTIVE: In January 2023, a rare event of collective inhalation paraquat poisoning occurred in Shandong, China. To analyze the clinical characteristics of an event of respiratory tract paraquat poisoning through inhalation.

METHODS: Clinical data from eight patients with paraquat inhalation poisoning were retrospectively analyzed.

RESULTS: The patients were mainly exposed to paraquat via the respiratory tract. The main clinical manifestations were ocular and respiratory irritation. Lung computed tomography (CT) showed that all eight patients had varying degrees of lung injury, mainly manifesting as exudative lesions. Laboratory tests revealed arterial blood gas hypoxemia, abnormal white blood cell count, and increased neutrophil ratio. Sufficient glucocorticoid impact therapy was effective, and all eight patients survived.

CONCLUSION: Eight patients experienced chest tightness, shortness of breath, and varying degrees of lung injury due to inhalation of paraquat through the respiratory tract. The early use of glucocorticoids and other comprehensive treatment measures, active prevention and treatment of lung infections, and protection of organ function have beneficial effects in such cases.

Language: en

Keywords

Humans; Dyspnea; Retrospective Studies; toxicology; *Lung Injury/pathology; *Paraquat; acute poisoning; case report; Lung/pathology; paraquat; respiratory