Citation

Thomas TJ, Pauze D, Love JN. J. Emerg. Med. 2008; 34(1): 71-75.

Affiliation

Department of Emergency Medicine, George Washington University, Washington, DC.

Copyright

(Copyright © 2008, Elsevier Publishing)

DOI

10.1016/j.jemermed.2007.03.051

PMID

17976801

Abstract

Lomotil(R) (Pfizer Inc., New York, NY) (diphenoxylate-atropine) is said to be potentially toxic to toddlers with exposure to as little as one to two tablets. A review of the data on diphenoxylate-atropine poisonings from the American Association of Poison Control Centers annual reports, review articles, and case series disputes this view. Fatalities associated with diphenoxylate-atropine have been reported in toddlers after repetitive or incorrect dosages. Fortunately, trends in pediatric diphenoxylate-atropine ingestions are decreasing.

Language: en