SAFETYLIT WEEKLY UPDATE

We compile citations and summaries of about 400 new articles every week.
RSS Feed

HELP: Tutorials | FAQ
CONTACT US: Contact info

Search Results

Journal Article

Citation

Erazo-Martinez V, Posso-Osorio I, Ruiz-Ordoñez I, Castro-Herrera F, Castaño-Valencia S, Delgado-Mora T, Cañas CA. Heliyon 2024; 10(5): e26768.

Copyright

(Copyright © 2024, Elsevier Publishing)

DOI

10.1016/j.heliyon.2024.e26768

PMID

38434332

PMCID

PMC10907710

Abstract

BACKGROUND: Snake envenomation is a medical condition with high morbidity and mortality in southwestern Colombia.

OBJECTIVES: To describe the characteristics of the envenomation caused by Viperidae snakes view in a highly complex hospital in Southwestern Colombia.

METHODS: A cross-sectional study was carried out. Patients treated for Viperidae snake envenomation from 2001 to 2020 in a Hospital Fundación Valle del Lili, Cali, Colombia, were studied.

RESULTS: Twenty-eight patients were included. Envenomation was caused by the genera Bothrops, Bothriechis, Porthidium, and Bothrocophias. The median age was 37.7 (±20.6), and they were predominantly male (19, 68%). Bites occurred on the upper extremities in 16 (57%) patients. Pain (23, 81%) and edema (22, 78%) were the most common clinical symptoms. Thirteen (46%) patients presented coagulopathy. Prolonged prothrombin and activated partial thromboplastin times were common: (22, 78% and 15, 53%, respectively). Twenty (71%) patients were treated with polyvalent antivenom (median dose of 6 (2-15) vials). The median time between the accident and antivenom administration was 9 h (5.5-17). Door-to-needle time was 37.5 (0-62) min. Eighteen (64%) patients were admitted to the intensive care unit. Three (11%) patients had serum sickness. Seven (25%) developed infectious complications, four (14%) had surgery, one (3%) had compartment syndrome, one (3%) underwent amputation of the affected limb, and one (3%) patient died.

CONCLUSIONS: Local manifestations and coagulopathy were common clinical features. Polyvalent antivenom was an effective treatment for disease control. Significant complications were associated with delays in seeking medical care.


Language: en

Keywords

Bothrops; Coagulopathy; Polyvalent antivenom; Snakebites; Viper

NEW SEARCH


All SafetyLit records are available for automatic download to Zotero & Mendeley
Print