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Journal Article

Citation

Mair C, Diez Roux AV, Shen M, Shea S, Seeman T, Echeverria SE, O'Meara ES. Ann. Epidemiol. 2009; 19(1): 49-57.

Affiliation

Center for Social Epidemiology and Population Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109-2029, USA.

Copyright

(Copyright © 2009, American College of Epidemiology, Publisher Elsevier Publishing)

DOI

10.1016/j.annepidem.2008.10.002

PMID

19064189

PMCID

PMC2763272

Abstract

PURPOSE: This study examined associations of neighborhood social cohesion, violence, and aesthetic quality with depressive symptoms among 2,619 healthy adults aged 45-84 years enrolled in the Multiethnic Study of Atherosclerosis. METHODS: Neighborhood characteristics were estimated by surveying a separate sample of area residents. Measures of aesthetic environment, social cohesion, and violence were combined into a summary score with increasing scores indicating more favorable environments. Depressive symptoms were measured using the Center for Epidemiologic Studies-Depression (CES-D) scale. Marginal maximum likelihood estimation was used to assess associations of neighborhood characteristics with CES-D score at baseline and with the odds of developing incident depression (CES-D score >/=16 or use of antidepressants) over a 4-5 year follow-up among persons with CES-D less than 16 at baseline. Models were adjusted for age, income, education, and race/ethnicity. RESULTS: Lower levels of social cohesion and aesthetic quality and higher levels of violence were associated with higher mean CES-D scores in men and women (P for trend <0.01, adjusted mean difference in CES-D per 1 SD increase in summary score -1.01 [95% confidence interval = -1.85, -0.17] and -1.08 [95% confidence interval = -1.88, -0.28] in men and women, respectively). Associations of neighborhood characteristics with incident depression were in the expected direction for women but confidence intervals were wide (odds ratio of incident depression = 0.89 [0.63, 1.26]). No association was seen for men (odds ratio = 0.96 [0.74, 1.25]). CONCLUSION: Neighborhood social cohesion, aesthetic quality, and violence are associated with the presence of depressive symptoms in residents.

Language: en

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