Citation

Shapiro JM, Belmaker RH, Biegon A, Seker A, Agam G. J. Neural. Transm. 2000; 107(5): 603-607.

Affiliation

Stanley Center for Bipolar Research, Ben-Gurion University of the Negev, Beersheva, Israel.

Copyright

(Copyright © 2000, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

11072754

Abstract

Inositol levels measured in postmortem brain of unipolar, bipolar and schizophrenic patients, suicide victims and normal controls showed no difference in scyllo-inositol levels in frontal or occipital cortex between any of the groups. We could not replicate previous reports of low myo-inositol levels in the frontal cortex of unipolar, bipolar and schizophrenic patients and suicide victims. There was no correlation between myo-inositol levels and estimated chlorpromazine equivalents in neuroleptic-treated subjects, and no effect of chronic haloperidol treatment on rat brain myo-inositol levels.

Language: en