Citation

Gupta S, Ahlawat SK. J. Toxicol. Clin. Toxicol. 1995; 33(1): 19-24.

Affiliation

Department of Medicine, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Copyright

(Copyright © 1995, Marcel Dekker)

DOI

unavailable

PMID

7837309

Abstract

Aluminum phosphide poisoning is common in the rural belt of Northern India. The release of cytotoxic phosphine gas primarily affects the heart, lungs, gastrointestinal tract and kidneys, although all organs can be involved. The cellular site of action of phosphine requires further definition. Diagnosis is made by clinical suspicion, silver nitrate test and biochemical examination of the gastric aspirate and viscera. Treatment consists of early gastric lavage, vasopressors and supportive care. Specific therapy with intravenous magnesium sulphate is recommended.

Language: en