Citation

Pavic L, Gregurek R, Petrović R, Petrović D, Varda R, Vukusić H, Crnković-Marković S. Eur. Arch. Psychiatry Clin. Neurosci. 2003; 253(2): 80-83.

Affiliation

Department of Diagnostic and Interventional Radiology, University Hospital Dubrava, Av. Gojka Suska 6, Zagreb, Croatia. Ladislav.pavic@zg.hinet.hr

Copyright

(Copyright © 2003, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00406-003-0411-z

PMID

12799745

Abstract

OBJECTIVE: We wanted to assess possible alterations in brain activation in PTSD patients with severe hyperarousal symptoms and impulsive aggressiveness. METHOD: 25 Croatian War (1991-1995) veterans with combat-related PTSD with severe hyperarousal symptoms and impulsive aggressiveness were assessed for possible alterations in cerebral blood flow in single photon emission computed tomography brain scans. RESULTS: Increased regional cerebral blood flow in projection area of nucleus accumbens was found in 13 of 25 subjects, and for all in the dominant brain hemisphere. DISCUSSION: We believe that at least some of PTSD symptoms, and especially the impulsive aggression, can be associated with increased regional cerebral blood flow in the projection area of nucleus accumbens.

Language: en