Citation

Yhede R, Blennow K, Forsman A, Soderstrom H. J. Neural. Transm. 2003; 110(12): 1369-1373.

Affiliation

Institute of Surgical Sciences, Göteborg University, Sweden.

Copyright

(Copyright © 2003, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00702-003-0073-z

PMID

14666409

Abstract

Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.

Language: en